10 Best “Botox in a Bottle” Products, According to Dermatologists
NewsletterSign InSearchSearchNewsletterBest of BeautyNewsSkinMakeupHairNailsWellnessShoppingAllure Beauty BoxNewsletterVideoWRINKLE WHISPERER10 “Botox in a Bottle” Skin-Care Products Derms Swear By for Fine LinesSmooth fine lines with these max-strength treatments, creams, and serums.By Christa Joanna LeeNovember 16, 2025Collage: Paula Balondo; Source images: Courtesy of brandsSave StorySave this storySave StorySave this storyIf you wince at the sight of sharp objects or don't have the cash to spend on in-office treatments, "Botox in a bottle" products have you covered—well, mostly, since no topical formula can create the same results as a professional treatment. These pain-free, comparatively inexpensive products, when used consistently and as directed, can deliver results similar to that of a loving jab in the face from your derm. Sure, nothing quite captures the effects of the nerve-freezing, muscle-paralyzing, skin-tightening power of botulinum toxin A (which sounds freakier than it is, we promise), but these formulas come pretty close. You can even use them in tandem with professional Botox treatments (from a board-certified dermatologist, of course) to enhance and prolong its line-dissipating benefits. Are topical creams as effective as Botox injections?What are the key ingredients in "Botox in a bottle" products?Meet the expertsHow we test and review productsOur staff and testersRead on for Allure editor- and dermatologist-approved finds to add to your skin-care routine that help target fine lines, sagging, and beyond. Allure contributing commerce editor Deanna Pai applying the SkinCeuticals P-Tiox serum