Are GLP-1s a Forever Medication?
NewBeauty Facebook Pinterest Instagram Youtube find a doctor Face Adult Acne Antioxidants Anti-Aging Celebrity Chronic Skin Conditions Eye Hydration Hyperpigmentation Makeup View All Eyebrows Eye Color Foundation Fragrance Lip Color Makeovers Male Skin Care Peels Pre-Event Prep Sensitive Skin Skin Care Skin Health Smile Sun Care Treatments Fillers Microneedling Post-Procedure Skin Care Neurotoxins Regenerative Aesthetics Skin Lifting Body Body Sculpting Breasts Butts Cellulite Hair Removal Hands + Nails Legs Pregnancy Find a Doctor Hair Bond Repair Celebrity Dry Hair Frizzy Hair Gray Hair Hair Color Hair Growth Hair Repair Scalp Health Styling + Tips Awards NB100 Awards 15th Annual Beauty Awards 2025 NewBeauty Readers’ Choice Awards Shopping Gift Guides Product Reviews NewBeauty Storefront Wellness Fitness GLP-1s Health Menopause About Us TESTTUBE Search for: Search HomeWellnessGLP-1s Are GLP-1s a Forever Medication? What experts want you to know before stopping treatment. Jessica Fields Published: Dec 16, 2025 The Good Brigade/ Getty Images In This Article Featured ExpertsWhat Happens in Your Body When You Stop Taking GLP-1sHow Your Face and Body Can Change After Stopping GLP-1sShould You Stay on GLP-1s Long-term?How to Safely Get Off of GLP-1s GLP-1 medications such as semaglutide and tirzepatide have surged in popularity for weight loss, and recent FDA regulations suggest that interest will only continue to grow. For people currently taking these medications, one question comes up again and again: Do you have to stay on GLP-1s long-term? The answer isn’t a simple yes or no. Medications like Ozempic, Wegovy and Mounjaro can be effective tools for weight loss, but what happens when you stop matters just as much as what happens while you’re on them. Understanding how your body responds on and off GLP-1s can help guide that decision. Ahead, we spoke with two medical professionals about what really happens when you discontinue a GLP-1 medication.