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Serena Williams on Turning to GLP-1s When Her Body Wouldn’t ‘Lose an Ounce’

Serena Williams on Turning to GLP-1s When Her Body Wouldn’t ‘Lose an Ounce’

NewBeauty Facebook Pinterest Instagram Youtube find a doctor Face Adult Acne Antioxidants Anti-Aging Celebrity Chronic Skin Conditions Eye Hydration Hyperpigmentation Makeup View All Eyebrows Eye Color Foundation Fragrance Lip Color Makeovers Male Skin Care Peels Pre-Event Prep Sensitive Skin Skin Care Skin Health Smile Sun Care Treatments Fillers Microneedling Post-Procedure Skin Care Neurotoxins Regenerative Aesthetics Skin Lifting Body Body Sculpting Breasts Butts Cellulite Hair Removal Hands + Nails Legs Pregnancy Find a Doctor Hair Bond Repair Celebrity Dry Hair Frizzy Hair Gray Hair Hair Color Hair Growth Hair Repair Scalp Health Styling + Tips Awards NB100 Awards 15th Annual Beauty Awards 2025 NewBeauty Readers’ Choice Awards Shopping Gift Guides Product Reviews NewBeauty Storefront Wellness Fitness GLP-1s Health Menopause About Us TESTTUBE Search for: Search HomeWellnessGLP-1s Serena Williams on Turning to GLP-1s When Her Body Wouldn’t ‘Lose an Ounce’ Plus, more candid takeaways from her conversation with Oprah. Tatiana Bido Published: Jan 15, 2026 Carlos Alvarez/Getty Images Serena Williams is speaking candidly about GLP-1 medications, this time alongside Oprah Winfrey. On a recent episode of The Oprah Podcast, the two discuss why Williams decided to go public with her experience and what shifted when her body stopped responding the way it once had. Winfrey opens the conversation by calling Williams’ decision a major moment, telling her she felt “so proud,” while acknowledging that criticism would follow. Williams makes it clear she isn’t worried about the backlash. “I don’t listen to the noise,” she tells Oprah. “Get in line. There’s a very long line all the way to the back.” She then describes a reality that lands differently coming from one of the most accomplished athletes of all time: despite training intensely, she still couldn’t lose weight. “My last match of the Open, I literally was working eight hours a day in…

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