The Best In-Office Treatments for Smile Lines
NewBeauty Facebook Pinterest Instagram Youtube find a doctor Face Adult Acne Antioxidants Anti-Aging Celebrity Chronic Skin Conditions Eye Hydration Hyperpigmentation Makeup View All Eyebrows Eye Color Foundation Fragrance Lip Color Makeovers Male Skin Care Peels Pre-Event Prep Sensitive Skin Skin Care Skin Health Smile Sun Care Treatments Fillers Microneedling Post-Procedure Skin Care Neurotoxins Regenerative Aesthetics Skin Lifting Body Body Sculpting Breasts Butts Cellulite Hair Removal Hands + Nails Legs Pregnancy Find a Doctor Hair Bond Repair Celebrity Dry Hair Frizzy Hair Gray Hair Hair Color Hair Growth Hair Repair Scalp Health Styling + Tips Awards NB100 Awards 15th Annual Beauty Awards 2025 NewBeauty Readers’ Choice Awards Shopping Gift Guides Product Reviews NewBeauty Storefront Wellness Fitness GLP-1s Health Menopause About Us TESTTUBE Search for: Search HomeCosmetic TreatmentsNeurotoxins The Best In-Office Treatments for Smile Lines What dermatologists recommend. Jessica Fields Published: Jan 13, 2026 Tatiana Maksimova / Getty Images In This Article Featured ExpertsWhat Causes Smile Lines?Best In-Office Treatments for Smile Lines Smile lines come with the territory of living your life: smiling, laughing and, yes, aging. For some people, they’re part of the charm. For others, they’re something they’d rather soften. The good news is there’s no one-size-fits-all way to treat them. From subtle surface tweaks to more intensive treatments that target deeper folds, there are plenty of options to address what you want. Ahead, we tapped two dermatologists to break down the most-requested treatments for smile lines. Nasolabial folds—often referred to as smile lines—are a natural part of facial movement. “They’re formed when we animate the face, whether that’s talking, smiling or a general change in expression,” says Alto, CA facial plastic surgeon Steven Curti, MD. While they’re always present, they tend to become more noticeable over time as the skin and underlying facial structure change.